Compute stability of outcome rate over time

Compute stability of outcome rate over time

computeTimeStability(
  studyPopulation,
  sccsModel = NULL,
  maxRatio = 1.25,
  alpha = 0.05
)

Arguments

studyPopulation

An object created using the createStudyPopulation() function.

sccsModel

Optional: A fitted SCCS model as created using fitSccsModel(). If the model contains splines for seasonality and or calendar time these will be adjusted for before computing stability.

maxRatio

The maximum global ratio between the observed and expected count.

alpha

The alpha (type 1 error) used to test for stability.

Value

A tibble with one row and three columns: ratio indicates the estimated mean ratio between observed and expected. p is the p-value against the null-hypothesis that the ratio is smaller than maxRatio, and stable is TRUE if p is greater than alpha.

Details

Computes for each month the observed and expected count, and computes the (weighted) mean ratio between the two. If splines are used to adjust for seasonality and/or calendar time, these adjustments are taken into consideration when considering the expected count. A one-sided p-value is computed against the null hypothesis that the ratio is smaller than maxRatio. If this p-value exceeds the specified alpha value, the series is considered stable.