The OHDSI Method Evaluation Benchmark - Negative Controls A set of 200 negative controls, centered around four outcomes of interest (acute pancreatitis, GI bleeding, Stroke, and IBD), and 4 exposures of interest (diclofenac, ciprofloxacin, metformin, and sertraline), which 25 negative controls each. Each drug-outcome pair also includes a comparator drug (where the comparator is also a negative control), allowing for evaluation of comparative effect estimation, and a nesting cohort for evaluating methods such as the nested case-control design. The exposure, outcome, and nesting cohorts can be created using the createReferenceSetCohorts function. These negative controls can form the basis to generate positive controls using the injectSignals function.

The OHDSI Method Evaluation Benchmark - Negative Controls A set of 200 negative controls, centered around four outcomes of interest (acute pancreatitis, GI bleeding, Stroke, and IBD), and 4 exposures of interest (diclofenac, ciprofloxacin, metformin, and sertraline), which 25 negative controls each. Each drug-outcome pair also includes a comparator drug (where the comparator is also a negative control), allowing for evaluation of comparative effect estimation, and a nesting cohort for evaluating methods such as the nested case-control design. The exposure, outcome, and nesting cohorts can be created using the createReferenceSetCohorts function. These negative controls can form the basis to generate positive controls using the injectSignals function.

data(ohdsiNegativeControls)

Format

A data frame with 200 rows and 9 variables:

targetId

Cohort ID identifying the target exposure

targetName

Name of the target cohort

comparatorId

Cohort ID identifying the comparator exposure

comparatorName

Name of the comparator cohort

nestingId

Cohort ID identifying the nesting cohort

nestingName

Name of the nesting cohort

outcomeId

Cohort ID identifying the outcome

outcomeName

Name of the outcome

type

THe type of control: exposure or outcome

targetConceptIds

A semi-colon separated list of concept IDs that together form the target exposure definitions.

comparatorConceptIds

A semi-colon separated list of concept IDs that together form the comparator exposure definitions.