Compute the minimum detectable relative risk

computeMdrr(population, alpha = 0.05, power = 0.8, twoSided = TRUE,
  modelType = "cox")

Arguments

population

A data frame describing the study population as created using the createStudyPopulation function. This should at least have these columns: subjectId, treatment, outcomeCount, timeAtRisk.

alpha

Type I error.

power

1 - beta, where beta is the type II error.

twoSided

Consider a two-sided test?

modelType

The type of outcome model that will be used. Possible values are "logistic", "poisson", or "cox". Currently only "cox" is supported.

Value

A data frame with the MDRR and some counts.

Details

Compute the minimum detectable relative risk (MDRR) and expected standard error (SE) for a given study population, using the actual observed sample size and number of outcomes. Currently, only computations for Cox models are implemented. For Cox model, the computations by Schoenfeld (1983) is used.

References

Schoenfeld DA (1983) Sample-size formula for the proportional-hazards regression model, Biometrics, 39(3), 499-503