Cohort diagnostics
a05_CohortDiagnostics.RmdIntroduction
In this example we’re going to summarise cohort diagnostics results for cohorts of individuals with an ankle sprain, ankle fracture, forearm fracture, or a hip fracture using the Eunomia synthetic data.
Again, we’ll begin by creating our study cohorts.
library(CDMConnector)
library(CohortConstructor)
library(CodelistGenerator)
library(PatientProfiles)
library(CohortCharacteristics)
library(PhenotypeR)
library(dplyr)
library(ggplot2)
con <- DBI::dbConnect(duckdb::duckdb(),
CDMConnector::eunomiaDir("synpuf-1k", "5.3"))
cdm <- CDMConnector::cdmFromCon(con = con,
cdmName = "Eunomia Synpuf",
cdmSchema = "main",
writeSchema = "main",
achillesSchema = "main")
cdm$injuries <- conceptCohort(cdm = cdm,
conceptSet = list(
"ankle_sprain" = 81151,
"ankle_fracture" = 4059173,
"forearm_fracture" = 4278672,
"hip_fracture" = 4230399
),
name = "injuries")Cohort diagnostics
We can run cohort diagnostics analyses for each of our overall cohorts like so:
cohort_diag <- cohortDiagnostics(cdm$injuries, match = TRUE)Our results will include a summary of the overlap between our cohorts. We could visualise this
plotCohortOverlap(cohort_diag, uniqueCombinations = TRUE)
Moreover, our results will also include a summary of the characteristics of each cohort, stratified by age group and sex.
tableCharacteristics(cohort_diag, groupColumn = c("age_group", "sex"))|
CDM name
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Eunomia Synpuf
|
||||||||||||||
| Variable name | Variable level | Estimate name |
Cohort name
|
|||||||||||
| ankle_fracture | ankle_sprain | forearm_fracture | hip_fracture | ankle_fracture_sampled | ankle_fracture_matched | ankle_sprain_sampled | ankle_sprain_matched | forearm_fracture_sampled | forearm_fracture_matched | hip_fracture_sampled | hip_fracture_matched | |||
| overall; overall | ||||||||||||||
| Number records | - | N | 0 | 28 | 0 | 0 | 0 | 0 | 27 | 27 | 0 | 0 | 0 | 0 |
| Number subjects | - | N | 0 | 27 | 0 | 0 | 0 | 0 | 26 | 27 | 0 | 0 | 0 | 0 |
| Cohort start date | - | Median [Q25 - Q75] | - | 2009-04-23 [2008-10-30 - 2010-02-02] | - | - | - | - | 2009-05-12 [2008-10-28 - 2010-02-18] | 2009-05-12 [2008-10-28 - 2010-02-18] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-09-13 | - | - | - | - | 2008-01-10 to 2010-09-13 | 2008-01-10 to 2010-09-13 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2009-04-24 [2008-10-30 - 2010-02-02] | - | - | - | - | 2009-05-12 [2008-10-28 - 2010-02-18] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-09-13 | - | - | - | - | 2008-01-10 to 2010-09-13 | 2010-10-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 72 [66 - 77] | - | - | - | - | 73 [66 - 78] | 73 [67 - 78] | - | - | - | - |
| Mean (SD) | - | 71.14 (15.68) | - | - | - | - | 72.19 (14.96) | 72.15 (14.91) | - | - | - | - | ||
| Range | - | 27 to 98 | - | - | - | - | 27 to 98 | 27 to 98 | - | - | - | - | ||
| Sex | Female | N (%) | - | 11 (39.29%) | - | - | - | - | 10 (37.04%) | 10 (37.04%) | - | - | - | - |
| Male | N (%) | - | 17 (60.71%) | - | - | - | - | 17 (62.96%) | 17 (62.96%) | - | - | - | - | |
| Prior observation | - | Median [Q25 - Q75] | - | 478 [303 - 762] | - | - | - | - | 497 [302 - 779] | 456 [292 - 726] | - | - | - | - |
| Mean (SD) | - | 499.54 (296.82) | - | - | - | - | 503.81 (301.59) | 476.70 (300.49) | - | - | - | - | ||
| Range | - | 9 to 986 | - | - | - | - | 9 to 986 | 9 to 986 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 572 [280 - 768] | - | - | - | - | 547 [278 - 775] | 598 [316 - 794] | - | - | - | - |
| Mean (SD) | - | 575.89 (301.07) | - | - | - | - | 570.89 (305.62) | 588.93 (302.92) | - | - | - | - | ||
| Range | - | 109 to 1,086 | - | - | - | - | 109 to 1,086 | 109 to 1,086 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 599 [317 - 794] | - | - | - | - |
| Mean (SD) | - | 1.11 (0.42) | - | - | - | - | 1.11 (0.42) | 589.93 (302.92) | - | - | - | - | ||
| Range | - | 1 to 3 | - | - | - | - | 1 to 3 | 110 to 1,087 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 31.00 [16.50 - 45.00] | - | - | - | - | 28.00 [14.00 - 45.00] | 17.00 [1.00 - 28.00] | - | - | - | - |
| Mean (SD) | - | 31.71 (20.36) | - | - | - | - | 31.22 (20.57) | 17.04 (17.18) | - | - | - | - | ||
| Range | - | 0.00 to 73.00 | - | - | - | - | 0.00 to 73.00 | 0.00 to 62.00 | - | - | - | - | ||
| 18 to 64; overall | ||||||||||||||
| Number records | - | N | - | 5 | - | - | - | - | 4 | 4 | - | - | - | - |
| Number subjects | - | N | - | 5 | - | - | - | - | 4 | 4 | - | - | - | - |
| Cohort start date | - | Median [Q25 - Q75] | - | 2009-09-08 [2009-01-19 - 2010-05-24] | - | - | - | - | 2010-01-15 [2009-04-15 - 2010-05-31] | 2010-01-15 [2009-04-15 - 2010-05-31] | - | - | - | - |
| Range | - | 2008-02-03 to 2010-06-19 | - | - | - | - | 2008-02-03 to 2010-06-19 | 2008-02-03 to 2010-06-19 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2009-09-08 [2009-01-19 - 2010-05-24] | - | - | - | - | 2010-01-15 [2009-04-15 - 2010-05-31] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-02-03 to 2010-06-19 | - | - | - | - | 2008-02-03 to 2010-06-19 | 2010-12-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 44 [43 - 56] | - | - | - | - | 50 [40 - 58] | 50 [40 - 58] | - | - | - | - |
| Mean (SD) | - | 46.60 (13.79) | - | - | - | - | 47.50 (15.76) | 47.50 (15.76) | - | - | - | - | ||
| Range | - | 27 to 63 | - | - | - | - | 27 to 63 | 27 to 63 | - | - | - | - | ||
| Sex | Female | N (%) | - | 2 (40.00%) | - | - | - | - | 1 (25.00%) | 1 (25.00%) | - | - | - | - |
| Male | N (%) | - | 3 (60.00%) | - | - | - | - | 3 (75.00%) | 3 (75.00%) | - | - | - | - | |
| Prior observation | - | Median [Q25 - Q75] | - | 616 [384 - 874] | - | - | - | - | 745 [470 - 880] | 745 [470 - 880] | - | - | - | - |
| Mean (SD) | - | 561.40 (362.64) | - | - | - | - | 605.75 (402.78) | 605.75 (402.78) | - | - | - | - | ||
| Range | - | 33 to 900 | - | - | - | - | 33 to 900 | 33 to 900 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 479 [221 - 711] | - | - | - | - | 350 [214 - 625] | 350 [214 - 625] | - | - | - | - |
| Mean (SD) | - | 533.60 (362.64) | - | - | - | - | 489.25 (402.78) | 489.25 (402.78) | - | - | - | - | ||
| Range | - | 195 to 1,062 | - | - | - | - | 195 to 1,062 | 195 to 1,062 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 351 [216 - 626] | - | - | - | - |
| Mean (SD) | - | 1.00 (0.00) | - | - | - | - | 1.00 (0.00) | 490.25 (402.78) | - | - | - | - | ||
| Range | - | 1 to 1 | - | - | - | - | 1 to 1 | 196 to 1,063 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 23.00 [5.00 - 26.00] | - | - | - | - | 14.00 [4.25 - 23.75] | 5.00 [0.75 - 16.25] | - | - | - | - |
| Mean (SD) | - | 20.20 (17.46) | - | - | - | - | 14.00 (12.25) | 12.00 (17.80) | - | - | - | - | ||
| Range | - | 2.00 to 45.00 | - | - | - | - | 2.00 to 26.00 | 0.00 to 38.00 | - | - | - | - | ||
| 65 to 150; overall | ||||||||||||||
| Number records | - | N | - | 23 | - | - | - | - | 23 | 23 | - | - | - | - |
| Number subjects | - | N | - | 22 | - | - | - | - | 22 | 23 | - | - | - | - |
| Cohort start date | - | Median [Q25 - Q75] | - | 2009-04-04 [2008-10-28 - 2009-12-27] | - | - | - | - | 2009-04-04 [2008-10-28 - 2009-12-27] | 2009-04-04 [2008-10-28 - 2009-12-27] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-09-13 | - | - | - | - | 2008-01-10 to 2010-09-13 | 2008-01-10 to 2010-09-13 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2009-04-05 [2008-10-28 - 2009-12-27] | - | - | - | - | 2009-04-05 [2008-10-28 - 2009-12-27] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-09-13 | - | - | - | - | 2008-01-10 to 2010-09-13 | 2010-10-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 75 [68 - 81] | - | - | - | - | 75 [68 - 81] | 74 [68 - 82] | - | - | - | - |
| Mean (SD) | - | 76.48 (10.03) | - | - | - | - | 76.48 (10.03) | 76.43 (9.97) | - | - | - | - | ||
| Range | - | 66 to 98 | - | - | - | - | 66 to 98 | 65 to 98 | - | - | - | - | ||
| Sex | Female | N (%) | - | 9 (39.13%) | - | - | - | - | 9 (39.13%) | 9 (39.13%) | - | - | - | - |
| Male | N (%) | - | 14 (60.87%) | - | - | - | - | 14 (60.87%) | 14 (60.87%) | - | - | - | - | |
| Prior observation | - | Median [Q25 - Q75] | - | 459 [302 - 726] | - | - | - | - | 459 [302 - 726] | 368 [292 - 700] | - | - | - | - |
| Mean (SD) | - | 486.09 (288.36) | - | - | - | - | 486.09 (288.36) | 454.26 (284.67) | - | - | - | - | ||
| Range | - | 9 to 986 | - | - | - | - | 9 to 986 | 9 to 986 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 598 [316 - 775] | - | - | - | - | 598 [316 - 775] | 636 [368 - 794] | - | - | - | - |
| Mean (SD) | - | 585.09 (294.69) | - | - | - | - | 585.09 (294.69) | 606.26 (290.18) | - | - | - | - | ||
| Range | - | 109 to 1,086 | - | - | - | - | 109 to 1,086 | 109 to 1,086 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 637 [370 - 794] | - | - | - | - |
| Mean (SD) | - | 1.13 (0.46) | - | - | - | - | 1.13 (0.46) | 607.26 (290.18) | - | - | - | - | ||
| Range | - | 1 to 3 | - | - | - | - | 1 to 3 | 110 to 1,087 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 40.00 [20.50 - 47.00] | - | - | - | - | 40.00 [20.50 - 47.00] | 17.00 [1.50 - 28.00] | - | - | - | - |
| Mean (SD) | - | 34.22 (20.41) | - | - | - | - | 34.22 (20.41) | 17.91 (17.32) | - | - | - | - | ||
| Range | - | 0.00 to 73.00 | - | - | - | - | 0.00 to 73.00 | 0.00 to 62.00 | - | - | - | - | ||
| overall; Female | ||||||||||||||
| Number records | - | N | - | 11 | - | - | - | - | 10 | 10 | - | - | - | - |
| Number subjects | - | N | - | 11 | - | - | - | - | 10 | 10 | - | - | - | - |
| Cohort start date | - | Median [Q25 - Q75] | - | 2008-12-02 [2008-03-30 - 2009-04-11] | - | - | - | - | 2008-11-13 [2008-03-29 - 2009-05-14] | 2008-11-13 [2008-03-29 - 2009-05-14] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-04-02 | - | - | - | - | 2008-01-10 to 2010-04-02 | 2008-01-10 to 2010-04-02 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2008-12-04 [2008-03-30 - 2009-04-11] | - | - | - | - | 2008-11-14 [2008-03-29 - 2009-05-14] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-04-02 | - | - | - | - | 2008-01-10 to 2010-04-02 | 2010-12-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 70 [66 - 74] | - | - | - | - | 70 [67 - 75] | 70 [67 - 74] | - | - | - | - |
| Mean (SD) | - | 70.09 (12.28) | - | - | - | - | 72.80 (8.82) | 72.70 (8.74) | - | - | - | - | ||
| Range | - | 43 to 92 | - | - | - | - | 63 to 92 | 63 to 92 | - | - | - | - | ||
| Sex | Female | N (%) | - | 11 (100.00%) | - | - | - | - | 10 (100.00%) | 10 (100.00%) | - | - | - | - |
| Prior observation | - | Median [Q25 - Q75] | - | 336 [88 - 466] | - | - | - | - | 317 [88 - 499] | 240 [88 - 349] | - | - | - | - |
| Mean (SD) | - | 342.91 (288.53) | - | - | - | - | 338.80 (303.79) | 265.60 (244.52) | - | - | - | - | ||
| Range | - | 9 to 822 | - | - | - | - | 9 to 822 | 9 to 812 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 742 [415 - 1,006] | - | - | - | - | 750 [349 - 1,007] | 778 [596 - 1,007] | - | - | - | - |
| Mean (SD) | - | 702.27 (325.00) | - | - | - | - | 701.40 (342.57) | 756.20 (303.79) | - | - | - | - | ||
| Range | - | 249 to 1,086 | - | - | - | - | 249 to 1,086 | 273 to 1,086 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 779 [597 - 1,008] | - | - | - | - |
| Mean (SD) | - | 1.18 (0.60) | - | - | - | - | 1.20 (0.63) | 757.20 (303.79) | - | - | - | - | ||
| Range | - | 1 to 3 | - | - | - | - | 1 to 3 | 274 to 1,087 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 28.00 [6.50 - 45.00] | - | - | - | - | 23.50 [5.25 - 44.50] | 3.00 [1.00 - 14.25] | - | - | - | - |
| Mean (SD) | - | 26.82 (20.58) | - | - | - | - | 25.00 (20.74) | 10.50 (14.84) | - | - | - | - | ||
| Range | - | 0.00 to 51.00 | - | - | - | - | 0.00 to 51.00 | 0.00 to 38.00 | - | - | - | - | ||
| overall; Male | ||||||||||||||
| Number records | - | N | - | 17 | - | - | - | - | 17 | 17 | - | - | - | - |
| Number subjects | - | N | - | 16 | - | - | - | - | 16 | 17 | - | - | - | - |
| Cohort start date | - | Median [Q25 - Q75] | - | 2009-10-08 [2009-01-03 - 2010-04-17] | - | - | - | - | 2009-10-08 [2009-01-03 - 2010-04-17] | 2009-10-08 [2009-01-03 - 2010-04-17] | - | - | - | - |
| Range | - | 2008-03-21 to 2010-09-13 | - | - | - | - | 2008-03-21 to 2010-09-13 | 2008-03-21 to 2010-09-13 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2009-10-08 [2009-01-03 - 2010-04-17] | - | - | - | - | 2009-10-08 [2009-01-03 - 2010-04-17] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-03-21 to 2010-09-13 | - | - | - | - | 2008-03-21 to 2010-09-13 | 2010-10-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 75 [66 - 79] | - | - | - | - | 75 [66 - 79] | 75 [66 - 80] | - | - | - | - |
| Mean (SD) | - | 71.82 (17.88) | - | - | - | - | 71.82 (17.88) | 71.82 (17.84) | - | - | - | - | ||
| Range | - | 27 to 98 | - | - | - | - | 27 to 98 | 27 to 98 | - | - | - | - | ||
| Sex | Male | N (%) | - | 17 (100.00%) | - | - | - | - | 17 (100.00%) | 17 (100.00%) | - | - | - | - |
| Prior observation | - | Median [Q25 - Q75] | - | 646 [368 - 837] | - | - | - | - | 646 [368 - 837] | 646 [368 - 837] | - | - | - | - |
| Mean (SD) | - | 600.88 (262.41) | - | - | - | - | 600.88 (262.41) | 600.88 (262.41) | - | - | - | - | ||
| Range | - | 80 to 986 | - | - | - | - | 80 to 986 | 80 to 986 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 449 [258 - 727] | - | - | - | - | 449 [258 - 727] | 401 [258 - 727] | - | - | - | - |
| Mean (SD) | - | 494.12 (262.41) | - | - | - | - | 494.12 (262.41) | 490.53 (263.48) | - | - | - | - | ||
| Range | - | 109 to 1,015 | - | - | - | - | 109 to 1,015 | 109 to 1,015 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 402 [259 - 728] | - | - | - | - |
| Mean (SD) | - | 1.06 (0.24) | - | - | - | - | 1.06 (0.24) | 491.53 (263.48) | - | - | - | - | ||
| Range | - | 1 to 2 | - | - | - | - | 1 to 2 | 110 to 1,016 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 34.00 [23.00 - 45.00] | - | - | - | - | 34.00 [23.00 - 45.00] | 23.00 [2.00 - 30.00] | - | - | - | - |
| Mean (SD) | - | 34.88 (20.18) | - | - | - | - | 34.88 (20.18) | 20.88 (17.69) | - | - | - | - | ||
| Range | - | 5.00 to 73.00 | - | - | - | - | 5.00 to 73.00 | 0.00 to 62.00 | - | - | - | - | ||
You can also visualise the age distribution:
tableCharacteristics(cohort_diag, groupColumn = c("age_group", "sex"))|
CDM name
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Eunomia Synpuf
|
||||||||||||||
| Variable name | Variable level | Estimate name |
Cohort name
|
|||||||||||
| ankle_fracture | ankle_sprain | forearm_fracture | hip_fracture | ankle_fracture_sampled | ankle_fracture_matched | ankle_sprain_sampled | ankle_sprain_matched | forearm_fracture_sampled | forearm_fracture_matched | hip_fracture_sampled | hip_fracture_matched | |||
| overall; overall | ||||||||||||||
| Number records | - | N | 0 | 28 | 0 | 0 | 0 | 0 | 27 | 27 | 0 | 0 | 0 | 0 |
| Number subjects | - | N | 0 | 27 | 0 | 0 | 0 | 0 | 26 | 27 | 0 | 0 | 0 | 0 |
| Cohort start date | - | Median [Q25 - Q75] | - | 2009-04-23 [2008-10-30 - 2010-02-02] | - | - | - | - | 2009-05-12 [2008-10-28 - 2010-02-18] | 2009-05-12 [2008-10-28 - 2010-02-18] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-09-13 | - | - | - | - | 2008-01-10 to 2010-09-13 | 2008-01-10 to 2010-09-13 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2009-04-24 [2008-10-30 - 2010-02-02] | - | - | - | - | 2009-05-12 [2008-10-28 - 2010-02-18] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-09-13 | - | - | - | - | 2008-01-10 to 2010-09-13 | 2010-10-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 72 [66 - 77] | - | - | - | - | 73 [66 - 78] | 73 [67 - 78] | - | - | - | - |
| Mean (SD) | - | 71.14 (15.68) | - | - | - | - | 72.19 (14.96) | 72.15 (14.91) | - | - | - | - | ||
| Range | - | 27 to 98 | - | - | - | - | 27 to 98 | 27 to 98 | - | - | - | - | ||
| Sex | Female | N (%) | - | 11 (39.29%) | - | - | - | - | 10 (37.04%) | 10 (37.04%) | - | - | - | - |
| Male | N (%) | - | 17 (60.71%) | - | - | - | - | 17 (62.96%) | 17 (62.96%) | - | - | - | - | |
| Prior observation | - | Median [Q25 - Q75] | - | 478 [303 - 762] | - | - | - | - | 497 [302 - 779] | 456 [292 - 726] | - | - | - | - |
| Mean (SD) | - | 499.54 (296.82) | - | - | - | - | 503.81 (301.59) | 476.70 (300.49) | - | - | - | - | ||
| Range | - | 9 to 986 | - | - | - | - | 9 to 986 | 9 to 986 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 572 [280 - 768] | - | - | - | - | 547 [278 - 775] | 598 [316 - 794] | - | - | - | - |
| Mean (SD) | - | 575.89 (301.07) | - | - | - | - | 570.89 (305.62) | 588.93 (302.92) | - | - | - | - | ||
| Range | - | 109 to 1,086 | - | - | - | - | 109 to 1,086 | 109 to 1,086 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 599 [317 - 794] | - | - | - | - |
| Mean (SD) | - | 1.11 (0.42) | - | - | - | - | 1.11 (0.42) | 589.93 (302.92) | - | - | - | - | ||
| Range | - | 1 to 3 | - | - | - | - | 1 to 3 | 110 to 1,087 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 31.00 [16.50 - 45.00] | - | - | - | - | 28.00 [14.00 - 45.00] | 17.00 [1.00 - 28.00] | - | - | - | - |
| Mean (SD) | - | 31.71 (20.36) | - | - | - | - | 31.22 (20.57) | 17.04 (17.18) | - | - | - | - | ||
| Range | - | 0.00 to 73.00 | - | - | - | - | 0.00 to 73.00 | 0.00 to 62.00 | - | - | - | - | ||
| 18 to 64; overall | ||||||||||||||
| Number records | - | N | - | 5 | - | - | - | - | 4 | 4 | - | - | - | - |
| Number subjects | - | N | - | 5 | - | - | - | - | 4 | 4 | - | - | - | - |
| Cohort start date | - | Median [Q25 - Q75] | - | 2009-09-08 [2009-01-19 - 2010-05-24] | - | - | - | - | 2010-01-15 [2009-04-15 - 2010-05-31] | 2010-01-15 [2009-04-15 - 2010-05-31] | - | - | - | - |
| Range | - | 2008-02-03 to 2010-06-19 | - | - | - | - | 2008-02-03 to 2010-06-19 | 2008-02-03 to 2010-06-19 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2009-09-08 [2009-01-19 - 2010-05-24] | - | - | - | - | 2010-01-15 [2009-04-15 - 2010-05-31] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-02-03 to 2010-06-19 | - | - | - | - | 2008-02-03 to 2010-06-19 | 2010-12-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 44 [43 - 56] | - | - | - | - | 50 [40 - 58] | 50 [40 - 58] | - | - | - | - |
| Mean (SD) | - | 46.60 (13.79) | - | - | - | - | 47.50 (15.76) | 47.50 (15.76) | - | - | - | - | ||
| Range | - | 27 to 63 | - | - | - | - | 27 to 63 | 27 to 63 | - | - | - | - | ||
| Sex | Female | N (%) | - | 2 (40.00%) | - | - | - | - | 1 (25.00%) | 1 (25.00%) | - | - | - | - |
| Male | N (%) | - | 3 (60.00%) | - | - | - | - | 3 (75.00%) | 3 (75.00%) | - | - | - | - | |
| Prior observation | - | Median [Q25 - Q75] | - | 616 [384 - 874] | - | - | - | - | 745 [470 - 880] | 745 [470 - 880] | - | - | - | - |
| Mean (SD) | - | 561.40 (362.64) | - | - | - | - | 605.75 (402.78) | 605.75 (402.78) | - | - | - | - | ||
| Range | - | 33 to 900 | - | - | - | - | 33 to 900 | 33 to 900 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 479 [221 - 711] | - | - | - | - | 350 [214 - 625] | 350 [214 - 625] | - | - | - | - |
| Mean (SD) | - | 533.60 (362.64) | - | - | - | - | 489.25 (402.78) | 489.25 (402.78) | - | - | - | - | ||
| Range | - | 195 to 1,062 | - | - | - | - | 195 to 1,062 | 195 to 1,062 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 351 [216 - 626] | - | - | - | - |
| Mean (SD) | - | 1.00 (0.00) | - | - | - | - | 1.00 (0.00) | 490.25 (402.78) | - | - | - | - | ||
| Range | - | 1 to 1 | - | - | - | - | 1 to 1 | 196 to 1,063 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 23.00 [5.00 - 26.00] | - | - | - | - | 14.00 [4.25 - 23.75] | 5.00 [0.75 - 16.25] | - | - | - | - |
| Mean (SD) | - | 20.20 (17.46) | - | - | - | - | 14.00 (12.25) | 12.00 (17.80) | - | - | - | - | ||
| Range | - | 2.00 to 45.00 | - | - | - | - | 2.00 to 26.00 | 0.00 to 38.00 | - | - | - | - | ||
| 65 to 150; overall | ||||||||||||||
| Number records | - | N | - | 23 | - | - | - | - | 23 | 23 | - | - | - | - |
| Number subjects | - | N | - | 22 | - | - | - | - | 22 | 23 | - | - | - | - |
| Cohort start date | - | Median [Q25 - Q75] | - | 2009-04-04 [2008-10-28 - 2009-12-27] | - | - | - | - | 2009-04-04 [2008-10-28 - 2009-12-27] | 2009-04-04 [2008-10-28 - 2009-12-27] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-09-13 | - | - | - | - | 2008-01-10 to 2010-09-13 | 2008-01-10 to 2010-09-13 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2009-04-05 [2008-10-28 - 2009-12-27] | - | - | - | - | 2009-04-05 [2008-10-28 - 2009-12-27] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-09-13 | - | - | - | - | 2008-01-10 to 2010-09-13 | 2010-10-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 75 [68 - 81] | - | - | - | - | 75 [68 - 81] | 74 [68 - 82] | - | - | - | - |
| Mean (SD) | - | 76.48 (10.03) | - | - | - | - | 76.48 (10.03) | 76.43 (9.97) | - | - | - | - | ||
| Range | - | 66 to 98 | - | - | - | - | 66 to 98 | 65 to 98 | - | - | - | - | ||
| Sex | Female | N (%) | - | 9 (39.13%) | - | - | - | - | 9 (39.13%) | 9 (39.13%) | - | - | - | - |
| Male | N (%) | - | 14 (60.87%) | - | - | - | - | 14 (60.87%) | 14 (60.87%) | - | - | - | - | |
| Prior observation | - | Median [Q25 - Q75] | - | 459 [302 - 726] | - | - | - | - | 459 [302 - 726] | 368 [292 - 700] | - | - | - | - |
| Mean (SD) | - | 486.09 (288.36) | - | - | - | - | 486.09 (288.36) | 454.26 (284.67) | - | - | - | - | ||
| Range | - | 9 to 986 | - | - | - | - | 9 to 986 | 9 to 986 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 598 [316 - 775] | - | - | - | - | 598 [316 - 775] | 636 [368 - 794] | - | - | - | - |
| Mean (SD) | - | 585.09 (294.69) | - | - | - | - | 585.09 (294.69) | 606.26 (290.18) | - | - | - | - | ||
| Range | - | 109 to 1,086 | - | - | - | - | 109 to 1,086 | 109 to 1,086 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 637 [370 - 794] | - | - | - | - |
| Mean (SD) | - | 1.13 (0.46) | - | - | - | - | 1.13 (0.46) | 607.26 (290.18) | - | - | - | - | ||
| Range | - | 1 to 3 | - | - | - | - | 1 to 3 | 110 to 1,087 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 40.00 [20.50 - 47.00] | - | - | - | - | 40.00 [20.50 - 47.00] | 17.00 [1.50 - 28.00] | - | - | - | - |
| Mean (SD) | - | 34.22 (20.41) | - | - | - | - | 34.22 (20.41) | 17.91 (17.32) | - | - | - | - | ||
| Range | - | 0.00 to 73.00 | - | - | - | - | 0.00 to 73.00 | 0.00 to 62.00 | - | - | - | - | ||
| overall; Female | ||||||||||||||
| Number records | - | N | - | 11 | - | - | - | - | 10 | 10 | - | - | - | - |
| Number subjects | - | N | - | 11 | - | - | - | - | 10 | 10 | - | - | - | - |
| Cohort start date | - | Median [Q25 - Q75] | - | 2008-12-02 [2008-03-30 - 2009-04-11] | - | - | - | - | 2008-11-13 [2008-03-29 - 2009-05-14] | 2008-11-13 [2008-03-29 - 2009-05-14] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-04-02 | - | - | - | - | 2008-01-10 to 2010-04-02 | 2008-01-10 to 2010-04-02 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2008-12-04 [2008-03-30 - 2009-04-11] | - | - | - | - | 2008-11-14 [2008-03-29 - 2009-05-14] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-01-10 to 2010-04-02 | - | - | - | - | 2008-01-10 to 2010-04-02 | 2010-12-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 70 [66 - 74] | - | - | - | - | 70 [67 - 75] | 70 [67 - 74] | - | - | - | - |
| Mean (SD) | - | 70.09 (12.28) | - | - | - | - | 72.80 (8.82) | 72.70 (8.74) | - | - | - | - | ||
| Range | - | 43 to 92 | - | - | - | - | 63 to 92 | 63 to 92 | - | - | - | - | ||
| Sex | Female | N (%) | - | 11 (100.00%) | - | - | - | - | 10 (100.00%) | 10 (100.00%) | - | - | - | - |
| Prior observation | - | Median [Q25 - Q75] | - | 336 [88 - 466] | - | - | - | - | 317 [88 - 499] | 240 [88 - 349] | - | - | - | - |
| Mean (SD) | - | 342.91 (288.53) | - | - | - | - | 338.80 (303.79) | 265.60 (244.52) | - | - | - | - | ||
| Range | - | 9 to 822 | - | - | - | - | 9 to 822 | 9 to 812 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 742 [415 - 1,006] | - | - | - | - | 750 [349 - 1,007] | 778 [596 - 1,007] | - | - | - | - |
| Mean (SD) | - | 702.27 (325.00) | - | - | - | - | 701.40 (342.57) | 756.20 (303.79) | - | - | - | - | ||
| Range | - | 249 to 1,086 | - | - | - | - | 249 to 1,086 | 273 to 1,086 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 779 [597 - 1,008] | - | - | - | - |
| Mean (SD) | - | 1.18 (0.60) | - | - | - | - | 1.20 (0.63) | 757.20 (303.79) | - | - | - | - | ||
| Range | - | 1 to 3 | - | - | - | - | 1 to 3 | 274 to 1,087 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 28.00 [6.50 - 45.00] | - | - | - | - | 23.50 [5.25 - 44.50] | 3.00 [1.00 - 14.25] | - | - | - | - |
| Mean (SD) | - | 26.82 (20.58) | - | - | - | - | 25.00 (20.74) | 10.50 (14.84) | - | - | - | - | ||
| Range | - | 0.00 to 51.00 | - | - | - | - | 0.00 to 51.00 | 0.00 to 38.00 | - | - | - | - | ||
| overall; Male | ||||||||||||||
| Number records | - | N | - | 17 | - | - | - | - | 17 | 17 | - | - | - | - |
| Number subjects | - | N | - | 16 | - | - | - | - | 16 | 17 | - | - | - | - |
| Cohort start date | - | Median [Q25 - Q75] | - | 2009-10-08 [2009-01-03 - 2010-04-17] | - | - | - | - | 2009-10-08 [2009-01-03 - 2010-04-17] | 2009-10-08 [2009-01-03 - 2010-04-17] | - | - | - | - |
| Range | - | 2008-03-21 to 2010-09-13 | - | - | - | - | 2008-03-21 to 2010-09-13 | 2008-03-21 to 2010-09-13 | - | - | - | - | ||
| Cohort end date | - | Median [Q25 - Q75] | - | 2009-10-08 [2009-01-03 - 2010-04-17] | - | - | - | - | 2009-10-08 [2009-01-03 - 2010-04-17] | 2010-12-31 [2010-12-31 - 2010-12-31] | - | - | - | - |
| Range | - | 2008-03-21 to 2010-09-13 | - | - | - | - | 2008-03-21 to 2010-09-13 | 2010-10-31 to 2010-12-31 | - | - | - | - | ||
| Age | - | Median [Q25 - Q75] | - | 75 [66 - 79] | - | - | - | - | 75 [66 - 79] | 75 [66 - 80] | - | - | - | - |
| Mean (SD) | - | 71.82 (17.88) | - | - | - | - | 71.82 (17.88) | 71.82 (17.84) | - | - | - | - | ||
| Range | - | 27 to 98 | - | - | - | - | 27 to 98 | 27 to 98 | - | - | - | - | ||
| Sex | Male | N (%) | - | 17 (100.00%) | - | - | - | - | 17 (100.00%) | 17 (100.00%) | - | - | - | - |
| Prior observation | - | Median [Q25 - Q75] | - | 646 [368 - 837] | - | - | - | - | 646 [368 - 837] | 646 [368 - 837] | - | - | - | - |
| Mean (SD) | - | 600.88 (262.41) | - | - | - | - | 600.88 (262.41) | 600.88 (262.41) | - | - | - | - | ||
| Range | - | 80 to 986 | - | - | - | - | 80 to 986 | 80 to 986 | - | - | - | - | ||
| Future observation | - | Median [Q25 - Q75] | - | 449 [258 - 727] | - | - | - | - | 449 [258 - 727] | 401 [258 - 727] | - | - | - | - |
| Mean (SD) | - | 494.12 (262.41) | - | - | - | - | 494.12 (262.41) | 490.53 (263.48) | - | - | - | - | ||
| Range | - | 109 to 1,015 | - | - | - | - | 109 to 1,015 | 109 to 1,015 | - | - | - | - | ||
| Days in cohort | - | Median [Q25 - Q75] | - | 1 [1 - 1] | - | - | - | - | 1 [1 - 1] | 402 [259 - 728] | - | - | - | - |
| Mean (SD) | - | 1.06 (0.24) | - | - | - | - | 1.06 (0.24) | 491.53 (263.48) | - | - | - | - | ||
| Range | - | 1 to 2 | - | - | - | - | 1 to 2 | 110 to 1,016 | - | - | - | - | ||
| Number visits prior year | - | Median [Q25 - Q75] | - | 34.00 [23.00 - 45.00] | - | - | - | - | 34.00 [23.00 - 45.00] | 23.00 [2.00 - 30.00] | - | - | - | - |
| Mean (SD) | - | 34.88 (20.18) | - | - | - | - | 34.88 (20.18) | 20.88 (17.69) | - | - | - | - | ||
| Range | - | 5.00 to 73.00 | - | - | - | - | 5.00 to 73.00 | 0.00 to 62.00 | - | - | - | - | ||