| Problem Specification |
When is prediction suitable in observational data? |
Guidelines needed |
| Data Creation |
Comparison of cohort vs case-control design |
Journal
of Big Data |
| Data Creation |
Addressing loss to follow-up (right censoring) |
BMC
medical informatics and decision makingk |
| Data Creation |
Investigating how to address left censoring in features
construction |
BMC
Medical Research Methodology |
| Data Creation |
Impact of over/under-sampling |
Paper under review |
| Data Creation |
Impact of phenotypes |
Study Done - Paper submitted |
| Model development |
How much data do we need for prediction - Learning curves at
scale |
International
Journal of Medical Informatics |
| Model development |
What impact does test/train/validation design have on model
performance |
BMJ
Open |
| Model development |
What is the impact of the classifier |
JAMIA |
| Model development |
Can we find hyper-parameter combinations per classifier that
consistently lead to good performing models when using claims/EHR
data? |
Study needs to be done |
| Model development |
Can we use ensembles to combine different algorithm models within a
database to improve models transportability? |
Study Complete |
| Model development |
Can we use ensembles to combine models developed using different
databases to improve models transportability? |
BMC
Medical Informatics and Decision Making |
| Evaluation |
How should we present model performance? (e.g., new
visualizations) |
JAMIA
Open |
| Evaluation |
How to interpret external validation performance (can we figure out
why the performance drops or stays consistent)? |
Study needs to be done |
| Evaluation |
Recalibration methods |
Study needs to be done |
| Evaluation |
Is there a way to automatically simplify models? |
Study
protocol under development |
