Plot posterior density per database
plotPerDbPosterior(
estimate,
showEstimate = TRUE,
dataCutoff = 0.01,
fileName = NULL
)
An object as generated using the computeBayesianMetaAnalysis()
function.
Show the parameter estimates (mode) and 95 percent confidence intervals?
This fraction of the data at both tails will be removed.
Name of the file where the plot should be saved, for example 'plot.png'. See the function ggplot2::ggsave in the ggplot2 package for supported file formats.
A Ggplot object. Use the ggplot2::ggsave function to save to file.
Plot the density of the posterior distribution of the theta parameter (the estimated log hazard ratio) at each site.
# Simulate some data for this example:
populations <- simulatePopulations()
# Fit a Cox regression at each data site, and approximate likelihood function:
fitModelInDatabase <- function(population) {
cyclopsData <- Cyclops::createCyclopsData(Surv(time, y) ~ x + strata(stratumId),
data = population,
modelType = "cox"
)
cyclopsFit <- Cyclops::fitCyclopsModel(cyclopsData)
approximation <- approximateLikelihood(cyclopsFit, parameter = "x", approximation = "custom")
return(approximation)
}
approximations <- lapply(populations, fitModelInDatabase)
approximations <- do.call("rbind", approximations)
# At study coordinating center, perform meta-analysis using per-site approximations:
estimate <- computeBayesianMetaAnalysis(approximations)
#> Detected data following custom parameric distribution
#> Performing MCMC. This may take a while
plotPerDbPosterior(estimate)