Table Name: Drug Exposure

The DRUG_EXPOSURE table will house records from PATBILL and PATCPT that have been mapped to the drug or metadata domain.

Administrations of drugs are recorded in the PATBILL table as standard charges. Premier captures the date of administration in the SERV_DATE field. Procedure drugs reside in the PATCPT table. DRUG_EXPOSURE_START_DATE for procedures is the last day of visit or VISIT_END_DATE, since dates for the administration of procedure drugs is not recorded, the assumption is made that the procedure occurred sometime before the end of the visit. DRUG_EXPOSURE_END_DATE cannot be determined because the patient is not followed each stay and days’ supply information is not available.

Premier does not provide NDC codes for drugs that are administered during a visit. The PRESCRIBING_PROVIDER_ID is determined from the visit using the admitting provider id of the visit. In Premier, the admitting and attending providers are provided and due to the similarity of both the fields, the admitting provider id is used. The determination cannot be made if the admitting provider was the provider that prescribed the medication but that is the only information that is available. Drug type is considered inpatient administration for all drugs, except those drugs that are procedures and come from PATCPT. Both HCPCS codes and CPT codes are available in PATCPT. The quantity of drugs administered as captured from the QTY field in PATBILL.

Each standard charge from PATBILL maps to the CHGMSTR table that houses additional information regarded the department, and descriptions about the item. To map each drug to an appropriate concept, USAGI was used to map STD_CHG_DESC to the value of an RxNorm concept. The CHGMSTR table is segmented by the department STD_DEPT_DESC. The drug records represented in this table are captured from the Pharmacy department. Any mapping that cannot be correctly identified is mapped to a CONCEPT_ID of zero. All drugs will be mapped and included in this table even if they don’t have a valid concept. All charges are loaded into the SOURCE_TO_CONCEPT_MAP table, and the table is attached in the appendix. The STD_CHG_CODE is mapped to a HOSP_CHG using the table HOSPCHG, and each HOSP_CHG has a description that is displayed in the CDM as the source value.

Only records that fall within an OBSERVATION_PERIOD are available for each person. The VISIT_OCCURRENCE table must be created before the DRUG_EXPOSURE table is created.

The field mapping is performed as follows:

Destination Field Source Field Applied Rule Comment
DRUG_EXPOSURE_ID - System generated  
PERSON_ID PAT.MEDREC_KEY    
DRUG_CONCEPT_ID PATCPT.CPT_CODE
PATBILL.STD_CHG_CODE
QUERY for PATCPT: SOURCE TO STANDARD: SELECT TARGET_CONCEPT_ID FROM CTE_VOCAB_MAP WHERE SOURCE_VOCABULARY_ID IN (‘CPT4’, ‘HCPCS’) AND TARGET_DOMAIN_ID = ‘Drug’

QUERY for PATBILL: SOURCE TO STANDARD: SELECT TARGET_CONCEPT_ID FROM CTE_VOCAB_MAP WHERE SOURCE_VOCABULARY_ID IN (‘JNJ_PMR_DRUG_CHRG_CD’) AND TARGET_DOMAIN_ID = ‘Drug’
 
Include all concepts that map to a concept id of zero.      
DRUG_EXPOSURE_START_DATE PATBILL.SERV_DATE VISIT_OCCURRENCE.VISIT_START_DATE Or VISIT_OCCURRENCE.VISIT_END_DATE If drug is from PATBILL use SERV_DATE
If drug comes from PATCPT then use visit end date
 
DRUG_EXPOSURE_START_DATETIME - NULL  
DRUG_EXPOSURE_END_DATE DRUG_EXPOSURE.DRUG_EXPOSURE_START_DATE DRUG_EXPOSURE.DRUG_EXPOSURE_START_DATE Now a required field. No info on days supply, so set same date as drug_exposure_start_date
DRUG_EXPSURE_END_DATETIME - NULL  
VERBATIM_END_DATE - NULL  
DRUG_TYPE_CONCEPT_ID   All records within the drug_exposure table should have a drug_type_concept_id = 32875 (Provider financial system)  
STOP_REASON - NULL  
REFILLS - NULL  
QUANTITY PATBILL.STD_QTY   Value is applied only to records that come from PATBILL, else records from PATCPT or PATICD are NULL
DAYS_SUPPLY - NULL  
SIG - NULL  
ROUTE_CONCEPT_ID - NULL  
LOT_NUMBER - NULL  
PROVIDER_ID PAT.ADMPHY NULL  
VISIT_OCCURRENCE_ID PAT.PAT_KEY    
DRUG_SOURCE_VALUE   For PATBILL table:
SELECT SOURCE_VALUE FROM (SELECT CONCAT(STD_CHG_DESC, ‘ / ‘, HOSP_CHG_DESC) AS SOURCE_VALUE FROM PATBILL A
JOIN CHGMSTR B ON A.STD_CHG_CODE=B.STD_CHG_CODE
JOIN hospchg C ON A.hosp_chg_id=C.hosp_chg_id ) A

for PATCPT table:
PATCPT.CPT_CODE
 
DRUG_SOURCE_CONCEPT_ID - NULL  
ROUTE_SOURCE_VALUE - NULL  
DOSE_UNIT_SOURCE_VALUE - NULL  

Change Log:

  • 2021.08.11: Updated DRUG_TYPE_CONCEPT_ID to leverage standard concept id.
  • 2023.08.29: PATCPT uses (‘cpt4’, ‘hcpcs’) as source codes, PATBILL uses ‘JNJ_PMR_DRUG_CHRG_CD’ as source codes, NO MIXING UP, since there’s intersection between (‘cpt4’, ‘hcpcs’) and ‘JNJ_PMR_DRUG_CHRG_CD’ codes. Added PATCPT.CPT_CODE as drug_source_value

Please contact Clair Blacketer (https://github.com/clairblacketer) if you have any questions